Analysis of the risk factors of local tumor progression after liver cancer patients treated with microwave ablation

ObjectiveTo analyze the risk factors of local tumor progression(LTP) after liver cancer patients treated with ultrasound-guided percutaneous microwave ablation(MWA).

MethodsA total of 102 lesions in 73 cases of liver cancer treated with MWA were investigated.The clinical data of the patients and postoperative following-up imaging examination data were retrospectively analyzed.

ResultsThe total incidence rate of LTP was 15.68%(16/102).The results of univariate analysis showed that the LTP was not related to the age, tumor type, and Child-Pugh classification of liver(P>0.05), and related to the tumor size, clear tumor boundary, tumor adjacence to large blood vessels and tumor blood perfusion degree(P < 0.05 to P < 0.01).The results of further multivariate logistic regression analysis showed that the tumor size >3 cm and tumor adjacence to large blood vessels were the independent risk factors of LTP(P < 0.05).

ConclusionsThe tumor size >3 cm and adjacence to large blood vessels are the independent risk factors of LTP after liver cancer patients treated with MWA.The corresponding measures and strategies should be taken to improve the efficacy of MWA in clinic.