Clinical efficacy of radiofrequency ablation in the treatment of atrial fibrillation and the predictive value of C reactive protein for long-term adverse events

ObjectiveTo compare the incidence rate of long-term adverse events between radiofrequency ablation and oral drug therapy for atrial fibrillation(AF), and further analyze the predictive value of C reactive protein(CRP) in long-term adverse events of AF patients.

MethodsThe patients with AF in the First Affiliated Hospital of Bengbu Medical College were selected, 89 patients were treated with catheter ablation, and 107 patients were treated with oral medication.Two groups were followed up for 18 months, and the incidence rate of chronic stroke, bleeding events and all-cause death in two groups were evaluated.The indicators in two groups were evaluated according to the pre-admission related indicators.The Cox regression analysis was used to predict the risk factors of long-term adverse events, and whether CRP for a predictor of AF long-term adverse events was evaluated.

ResultsThe long-term stroke, bleeding events, all-cause death and all events in the patients treated with radiofrequency ablation were less than those in the patients treated with drug.The adverse events time in the radiofrequency ablation group was little compared with in the drug therapy group, but the difference of which was not statistically significant(P>0.05).The CRP was an independent predictor of long-term adverse events in AF patients, and the serum CRP ≥ 6.4 mL/L was associated with the incidence rate of long-term adverse events in AF patients.

ConclusionsThe CRP level can be used as a predictor of long-term adverse events, and the high-risk population of patients with AF can be screened using CRP level.