DU Chao-jun, DING Li, LI Hong-xin, GUO Wen-bin, WU Peng-peng, MA Jia-jia. Study on the clinical effects and prognosis of minimally invasive transthoracic occlusion guided by esophageal ultrasound in the treatment of ventricular septal defect in children[J]. Journal of Bengbu Medical University, 2021, 46(5): 645-648. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.022
    Citation: DU Chao-jun, DING Li, LI Hong-xin, GUO Wen-bin, WU Peng-peng, MA Jia-jia. Study on the clinical effects and prognosis of minimally invasive transthoracic occlusion guided by esophageal ultrasound in the treatment of ventricular septal defect in children[J]. Journal of Bengbu Medical University, 2021, 46(5): 645-648. DOI: 10.13898/j.cnki.issn.1000-2200.2021.05.022

    Study on the clinical effects and prognosis of minimally invasive transthoracic occlusion guided by esophageal ultrasound in the treatment of ventricular septal defect in children

    • ObjectiveTo compare the clinical effects between minimally invasive transthoracic occlusion guided by esophageal ultrasound and conventional repair in the treatment of ventricular septal defect(VSD) in children.
      MethodsEighty-nine VSD children treated with traditional thoracotomy repair and 85 VSD children treated with minimally invasive transthoracic occlusion guided by esophageal ultrasound were divided into the control group and observation group, respectively.The surgical situation, postoperative inflammatory factors, postoperative complications, postoperative recovery time and cardiac function indexes were compared between two groups.
      ResultsThe operation time in observation group was shorter than that in control group(P < 0.01), and the intraoperative blood transfusion amount in observation group(0 mL) was less than that in control group(407.87±95.89)mL(P < 0.01).On the postoperative 1 to 3 days, the C-reactive protein level and leukocyte count in observation group were lower than those in control group(P < 0.01).The difference of the total incidence rate of postoperative complication between two groups was not statistically significant(P>0.05).The intubation time and hospital stay in observation group were shorter than those in control group(P < 0.01).After operation, the levels of LVEF, LVEDD and LVESD in two groups were significantly improved compared with those before operation(P < 0.01).After operation, the level of LVEF in observation group was higher than that in control group, and the levels of LVEDD and LVESD in observation group were lower than those in control group(P < 0.01).
      ConclusionsThe minimally invasive transthoracic occlusion guided by esophageal ultrasound in treating VSD of children can significantly shorten the operation time and reduce intraoperative blood transfusion amount.It is beneficial to reduce postoperative inflammatory reaction, reduce the risk of postoperative complications, accelerate the progress of postoperative rehabilitation and improve cardiac function.
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