Clinical study on the efficacy and short-term prognosis of Xinmailong injection in the treatment of chronic heart failure

ObjectiveTo explore the efficacy and short-term prognosis of Xinmailong injection in the treatment of chronic heart failure.

MethodsEighty-six patients with chronic heart failure were randomly divided into the study group(43 cases) and control group(43 cases).The control group was treated with the ACE inhibitor, angiotensin Ⅱ receptor antagonist, diuretic, cardiotonic agent, and β-receptor blocker.On the basis of the medication of the control group, the study group was additionally treated with Xinmailong injection.The 6-miniute walking distance, NT-probNP level, left ventricular ejection fraction(LVEF/%), MLHFQ score and MACE incidence were compared between two groups.

ResultsAfter two courses of treatment, the 6-minute walking distance and LVEF/% in study group were significantly higher those in control group(P < 0.01).The NT-proBNP level in study group was significantly lower than that in control group(P < 0.01).The treatment efficiency in study group was higher than that in control group(P < 0.05), and the MLHFQ score in study group was lowher than that in control group(P < 0.05).The incidence of major adverse cardiovascolar events in study group after 2 months of discharge was less than that in control group(P < 0.01).

ConclusionsXinmailong injection in the treatment of chronic heart failure has good curative effect and short-term prognosis of patients, which can provide a basis for clinical treatment.