Comparative study of the early oral nutrition and enteral nutrition via jejunal feeding tube in patients with gastric cancer after total gastrectomy

ObjectiveTo investigate the safety and feasibility of early oral nutrition in patients with gastric cancer after total gastrectomy.

MethodsThe gastric cancer patients treated with laparoscope-assisted radical gastrectomy were divided into the early oral nutrition group(no nutrition tube group, 25 cases) and enteral nutrition via jejunal feeding tube group(nutrition tube group, 23 cases) according to different enteral nutrition modes.The incidence rate of postoperative complications, postoperative stress response indexes, postoperative nutrition indexes, postoperative intestinal barrier function indexes, postoperative exhaust time and postoperative hospital stay were analyzed and compared between two groups.

ResultsThere was no statistical significance in postoperative nutrition index, postoperative exhaust time and hospital stay between two groups(P>0.05).The incidence rates of postoperative throat pain and diarrhea in no nutrition group group were significantly better than those in nutrition tube group(P < 0.01 and P < 0.05), meanwhile the levels of C-reactive protein, D-lactic acid and I-FABP in feeding group were lower than those in nutrition tube group(P < 0.05 to P < 0.01).

ConclusionsFor gastric cancer patients treated with total gastrectomy, compared with enteral nutrition via nasal jejunal feeding tube, the early oral nutrition is safe, and can reduce the incidence rates of pharyngeal discomfort and diarrhea, reduce the stress response of the body, and promote the recovery of intestinal barrier function.