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    WANG Geng-ming, ZHOU Yan, SUN Qian, ZHOU Yu-fu, DING Jian-ming, ZHOU Shi-xiang, GUO Shu-nan, CHEN Man. Study on the clinical efficacy of radical radiotherapy in locally advanced hypopharyngeal carcinoma and prognostic factors[J]. Journal of Bengbu Medical University, 2021, 46(9): 1158-1160. DOI: 10.13898/j.cnki.issn.1000-2200.2021.09.002
    Citation: WANG Geng-ming, ZHOU Yan, SUN Qian, ZHOU Yu-fu, DING Jian-ming, ZHOU Shi-xiang, GUO Shu-nan, CHEN Man. Study on the clinical efficacy of radical radiotherapy in locally advanced hypopharyngeal carcinoma and prognostic factors[J]. Journal of Bengbu Medical University, 2021, 46(9): 1158-1160. DOI: 10.13898/j.cnki.issn.1000-2200.2021.09.002
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    Study on the clinical efficacy of radical radiotherapy in locally advanced hypopharyngeal carcinoma and prognostic factors

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      • Abstract
    • ObjectiveTo analyze the clinical effects of radical radiotherapy in the treatment of locally advanced hypopharyngeal cancer, and evaluate the prognostic factors.
      MethodsThe clinical data of 25 patients with locally advanced hypopharyngeal carcinoma from October 2016 to December 2018 were retrospectively analyzed.The overall survival of patients was calculated using Kaplan-Meier method.The Cox model was used for univariate analysis and multivariate analysis.
      ResultsThe recent effective rate was 100%.The median surviual time was 25 months.The 2-year surviual rate was 32.0%.The results of univariate analysis indicated that the N stage, clinical stage, recent effective rate and concurrent chemotherapy were the prognostic factors(P < 0.01).The results of multivariate analysis showed that the clinical stage and concurrent chemotherapy were the independent prognostic factors(P < 0.01 and P < 0.05).
      ConclusionsThe short-term effects of radical radiotherapy for locally advanced hypopharyngeal carcinoma is definite.The clinical stage and concurrent chemotherapy are the independent prognostic factors.
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