Significance of combined determination of serum lipase, amylase and C-reactive protein in the diagnosis of acute pancreatitis

ObjectiveTo explore the significance of lipase(LPS), amylase(AMS) and C-reactive protein(CRP) in the diagnosis of acute pancreatitis(AP).

MethodsThe levels of peripheral blood LPS, AMS and CRP in 70 AP patients and 30 non-AP patients were detected using dry chemical analyzer(VITROS 5600), and the data in two groups were analyzed.

ResultsThe serum levels of LPS, AMS and CRP in AP group were higher than those in control group(P < 0.01).The sensitivity and specificity of the combined detection of the two indicators were higher than that of the single detection.When the three indicators of AMS, LPS and CRP were combined, the diagnostic sensitivity and specificity of which reached 95.7% and 98.0%, and the area under the ROC curve of serum LPS and AMS was relatively high.

ConclusionsThe combined detection of serum LPS, AMS and CRP can effectively improve the diagnostic effects of AP, and which is worthy of clinical application.