Study on the PICC risk factors prediction of venous thrombosis in patients with hepatobiliary malignancies

ObjectiveTo investigate the incidence rate and risk factors of peripherally inserted central catheter(PICC) catheter-related thrombosis(CRT) in patients with hepatobiliary malignant tumors.

MethodsThe clinical data of 102 patients with hepatobiliary malignancies were retrospectively analyzed.The incidence rate of CRT was counted.The relationship between the baseline data, placement of PICC and CRT were analyzed using the single factor method, and the factors with statistical significance were included in the logistic regression model for analysis.

ResultsThe incidence rate of CRT was about 31.37%.The results of univariate analysis showed that no antiplatelet or anticoagulation history, smoking history, infection, distant metastasis, bone marrow suppression, abnormal rate of puncture site, BMI and catheter diameter in CRT group were higher tahn those in nonCRT group(P < 0.05 to P < 0.01).The results of multiple-factor analysis showed that the smoking, catheter diameter less than 4-F/5-F, myelosuppression, phlebitis and high BMI were the independent risk factors in patients with hepatobiliary malignant tumor complicated with CRT(P < 0.05 to P < 0.01).

ConclusionsThe CRT occurs predominantly in hepatobiliary malignancies patients treated with PICC for a long time, and the smoking, bone marrow suppression, abnormal puncture sites, phlebitis and catheter diameter less tahn 4-F/5-F are the independent risk factors of CRT in patients with hepatobiliary malignancies.