The relationship between clinical asthenia scale(CFS) and short-term prognosis of elderly patients with coronary heart disease

ObjectiveTo explore the relationship between clinical asthenia scale(CFS) and short-term prognosis in elderly patients with coronary heart disease(CAD).

MethodsOne hundred and twenty elderly CAD patients were treated with intervention, and the CFS scores of the patients before treatment were evaluated.According to the short-term prognosis, the patients were divided into the good prognosis group(survivors without events) and poor prognosis group(death or serious adverse event patients).The CFS score between two groups was compared, and the receiver operating characteristic curve(ROC) was drawn to analyze the predictive value of CFS score for the poor short-term prognosis of elderly CAD patients, and the area under the curve(AUC) and optimal boundary value were determined.According to the CFS score, the patients were divided into the weak group and nonweak group, and the relationship between frailty and patients' clinical characteristics were analyzed.

ResultsAmong 120 patients, the prognosis of 28(23.33%)patients were poor, and the prognosis of 92(76.67%) patients were good.Among 28 patients with poor prognosis, 4 cases(14.29%) died in hospital(including 3 cases with heart failure and 1 casewith cardiogenic shock), 9(32.14%) cases were urinary tract infection, 5(17.86%) cases were severe bleeding, and 10(35.71%) cases were upper respiratory tract infection.The CFS score in good prognosis group(4.13±0.56) was significantly lower than that in poor prognosis group(6.02±1.61)(P < 0.01).The AUC of CFS was 0.704(standard error=0.055, P < 0.01, 95% CI=0.597-0.811), and the optimal boundary value was 5.475.The differences of the types of disease and number of lesions between the weak group and nonweak group were statistically significant(P < 0.01), and the proportios of unstable angina pectoris, double-branch lesions and three-branch lesions in weak group were higher than those in nonweak group(P < 0.01).The differences of the lesion site, hyperlipidemia rate, diabetes rate, hypertension rate and smoking rate between weak group and nonweak group were not statistically significant(P>0.05).

ConclusionsCompared with the patients with good short-term prognosis, the CFS scores of e patients with poor prognosis significantly increase.The CFS score has a certain predictive value for the short-term prognosis of the elderly patients with CHD, and the CFS score may be affected by the type of CHD and number of lesions.