Analysis of influencing factors of SIRS after percutaneous nephrolithotomy based on log-binomial regression model

ObjectiveTo analyze the influencing factors of systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy based on log-binomial regression model.

MethodsEighty patients who underwent percutaneous nephrolithotomy were divided into SIRS group(n=23) and control group(n=57).The age, gender, ipsilateral stone operation history, preoperative indwelling double-J tube or not, preoperative urine culture, operation time, lithotomy channel, postoperative blood transfusion or not, stone diameter, postoperative residual stone and stone shape were set as independent variables, and postoperative SIRS or not was set as dependent variable to fit the log-binomial regression model.

ResultsUnivariate log-binomial regression analysis showed that preoperative urine culture, operation time, multi-channel lithotomy, postoperative blood transfusion, stone diameter and staghorn stone were the influencing factors of SIRS after percutaneous nephrolithotomy(P < 0.01).The patients with positive urine culture before operation, operation time >60 min, multi-channel lithotomy, postoperative blood transfusion, stone diameter ≥ 50 mm and staghorn stone had higher risk of SIRS(P < 0.01), and the prevalence ratio was 2.14, 2.33, 2.85, 2.65 and 2.59, respectively.

ConclusionsThe occurrence of SIRS after percutaneous nephrolithotomy is due to multiple factors.It should be paid more attention to the patients with positive urine culture before operation, operation time >60 min, multi-channel lithotomy, stone diameter ≥ 50 mm and staghorn stone in clinic.