Study on the application value of tranexamic acid combined with autologous blood resorption system in total hip arthroplasty

ObjectiveTo analyze the application effects of tranexamic acid combined with autologous blood resorption system in total hip arthroplasty.

MethodsEighty-four advanced femoral head necrosis patients(88 hips) treated with total hip arthroplasty were divided into the observation group(42 cases treated with tranexamic acid combined with autologous blood resorption system) and control group(43 cases treated with autologous blood resorption system).The operation time, intraoperative bleeding, auto blood resorption, postoperative drainage, intraoperative blood transfusion and postoperative blood routine in two groups were recorded.

ResultsThe differences of the operation time and autologous blood resorption system were not statistically significant between two groups(P>0.05).The intraoperative bleeding, postoperative drainage and intraoperative blood transfusion rate in observation group were significantly lower than those in control group(P < 0.01).The preoperative RBC, Hb and HCT levels in two groups were significantly higher than those after 1, 3 and 7 days of operation(P < 0.05).The differences in the levels of RBC, Hb and HCT before operation were not statistically significant between two groups(P>0.05).The levels of RBC and Hb after 1, 3 and 7 days of operation, and HCT levels after 1 and 7 days of operation in observation group were higher than those in control group(P < 0.01).The difference of the level of HCT after 3 days of operation was not statistically significant between two groups(P>0.05).

ConclusionsThe tranexamic acid combined with autologous blood resorption system can significantly reduce the blood loss of total hip arthroplasty, reduce the blood transfusion rate, promote the recovery and shorten the length of stay of patients.