Cognitive ability change in migraine patients and its correlation with depression and anxiety

ObjectiveTo investigate the cognitive changes of migraine patients and its relationship with anxiety and depression.

MethodsThe cognitive function in 151 patients with migraine were evaluated using the Montreal cognitive assessment, and the patients were divided into the cognitive decline group and normal cognitive group according to the cognitive function results.The clinical condition and mental state in two groups were evaluated using the general situation questionnaire, visual analog scale(VAS), headache impact test 6, self-evaluation of depression scale(SDS) and self-evaluation of anxiety scale(SAS).

ResultsAmong 151 migraine patients, 38 cases(25.2%) with cognitive impairment were found.The effects of intensity of headache on daily life were greater(P < 0.05).The differences of SDS score and SAS score between two groups were statistically significant(P < 0.05).The results of Spearman correlation analysis showed that the cognitive dysfunction was positively correlated with anxiety and depression(r=0.236, 0.281, P < 0.05).

ConclusionsAmong the migraine patients with cognitive dysfunction, the severity of headache and its impact on daily life are greater, and the cognitive impairment of migraine is clearly related to the depression and anxiety.