Efficacy of the sufentanil patient-controlled intravenous analgesia combined with anterior quadratus lumborum block in elderly lower limb surgery

ObjectiveTo investigate the value of sufentanil patient-controlled intravenous analgesia combined with anterior quadratus lumborum block in lower limb surgery in the elderly.

MethodsEighty-six elderly patients treated with lower limb surgery were divided into the observation group and control group by random number table method(43 cases in each group). After the operation, the affected side of the observation group received anterior quadratus lumborum block under the guidance of ultrasound, and 30 mL of 0.447% ropivacaine mesylate was injected. Two groups received patient-controlled intravenous analgesia of sufentanil. The static and motor visual analog scale(VAS), sufentanil dosage and delirium occurrence in two groups were analyzed after 6 h(T₁), 12 h(T₂), 24 h(T₃) and 48 h(T₄) of operation, and the maximum flexion and abduction of hip joint in two groups at T₂, T₃ and T₄ were observed. The levels of serum inflammatory factors(including tumor necrosis factor α(TNF-α), C reactive protein(CRP) and interleukin-6(IL-6) were compared between two groups on the next day after surgery, and the incidence rates of adverse reactions within 48 h after surgery in two groups were analyzed.

ResultsThe static and motor VAS scores, dosage of sufentanil and incidence rates of delirium in observation group were lower than those in control group at T₁, T₂, T₃ and T₄(P < 0.05 to P < 0.01). The maximum flexion and abduction of the hip joint in observation group at T₂, T₃ and T₄ were higher than those in control group(P < 0.01). The levels of TNF-α, CRP and IL-6 in observation group were lower than those in control group on the next day after operation(P < 0.01). The incidence rate of adverse reactions within 48 h after operation in observation group was lower than that in control group(P < 0.05).

ConclusionsThe sufentanil patient-controlled intravenous analgesia combined with anterior quadratus lumborum block in elderly lower limb surgery has a precise postoperative analgesia effect, which can reduce the postoperative sufentanil dosage, incidence rate of postoperative delirium, level of early serum inflammatory factors, and has high safety.