Application of platelet-rich fibrin combined with coronally advance flap in the treatment of gingival recession

Objective To compare the application effects between the platelet-rich fibrin(PRF) combined with coronally advanced flap(CAF) and coronally advanced flap alone in the treatment of gingival recession(GR).

Methods Thirty-six patients with GR were randomly divided into the observation group(18 cases, 25 teeth with GR) and control group(18 cases, 24 teeth with GR). The observation group and control group were treated with PRF combined with CAF and CAF, respectively. The microsurgery in two groups were used.The base line, and periodontal probing depth(PD), vertical gingival regression height(VGR), keratinized gingival width(KTH), gingival thickness(GT), patient comfort(PCS), sensitivity(HS), aesthetic index(PES) and total satisfaction after 3 and 6 months of operation in two groups were recorded and compared.

Results The differences of the PD and KTH in two groups between before and after operation were not statistically significant(P>0.05). In terms of root surface coverage, the difference of the VGR in two groups between before and after operation was statistically significant(P < 0.01). The difference of the GT in the observation group between before and after operation was statistically significant(P < 0.01). The differences of the patients' satisfaction(including the PCS, HS and PES) in the observation group were statistically significant between before and after surgery(P < 0.01), especially for HS, the patients were generally satisfied after surgery.

Conclusions The PRF membrane combined with CAF in the treatment of GR can achieve the good root surface coverage, and the postoperative GT and patient's satisfaction have more prominent advantages compared with the CAF alone.