Effect of protein-energy wasting on quality of life in maintenance hemodialysis patients with end-stage renal disease

ObjectiveTo study the effect of protein-energy wasting(PEW) on the prognosis of maintenance hemodialysis(MHD) patients.

MethodsA total of 150 patients with end-stage renal disease who were subject to MHD, were enrolled in the invstigation and divided into PEW group(n=33) and non-PEW group(n=117) according to the diagnosis critiria of PEW syndorome. The quality of life scores by KDQOLTM-36 scale in the two groups were compared and analyzed.

ResultsThirty-three cases met at least three diagnostic indexes of PEW with a percentage of 22.0%. The values of systolic blood pressure, diastolic blood pressure, heart rate, upper arm circumference, triceps skinfold thickness, hip circumference, grip strength, albumin and creatinine in PEW group were significantly lower than those in non-PEW group(P < 0.05);the time of dialysis in the PEW group was longer than that in the non-PEW group, and body mass index was lower than that in the non-PEW group(P < 0.05). There were significant differences in vitality, social function, social emotion, symptom influence, nephropathy influence and total score between PEW group and non PEW group(P < 0.05 to P < 0.01).

ConclusionsPEW is a common complication in end-stage renal disease patients receiving MHD and its impact on patients' quality of life should be given more attention.