ObjectiveTo explore the construction of a prediction model of psychological disorders in colorectal cancer patients with enterostomy.
MethodsA total of 290 colorectal cancer patients with enterostomy were investigated, and randomly set the training set(203 cases) and test set(87 cases). According to the Minnesota multiphasic personality inventory(MMPI), the patients were divided into the psychological disorder group(MMPI≥60 points) and non-psychological disorder group(MMPI < 60 points). The general data in the training set were compared between two groups, the related factors affecting the psychological disorders of colorectal cancer patients with enterostomy were analyzed using the logistic regression model. The R software was used to establish a nomogram prediction model based on the training set, and the effectiveness of model in the test set was evaluated.
ResultsTwo invalid questionnaires(one in the training set and one in the test set) were eliminated, and 288 valid questionnaires were obtained with effective recovery rate of 99.31%. Two hundred and two cases were included in the training set, and 67 cases(33.17%) in the psychological disorder group and 135 cases(66.83%) in the non-psychological disorder group were identified. The differences of the gender, enterostomy time, self-management ability score, social support rating scale(SSRS) score and enterostomy complications between two groups were statistically significant(P < 0.05 to P < 0.01). The results of multivariate logistic analysis showed that female, long time of enterostomy, high score of self-management ability and high score of SSRS were the protective factors of psychological disorders, and the enterostomy complication was the risk factor of psychological disorders in colorectal cancer patients with enterostomy(P < 0.05 to P < 0.01). The consistency index of the above factors in predicting psychological disorders in colorectal cancer patients with enterostomy was 0.804(95%CI: 0.743-0.857). The results of further verification by ROC curve showed that the specificity was 88.50%, and the sensitivity was 81.60%. The results of external validation showed that the sensitivity and specificity of this model were 85.71% and 87.93%, respectively.
ConclusionsThe psychological disorder of colorectal cancer patients with enterostomy is more severe. The gender, self-management ability, social support, enterostomy complications and time are the influencing factors of psychological disorder. The prediction model has high application value.
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