ObjectiveTo explore the correlation between the total urea clearance index(Kt/V) and abdominal aortic calcification(AAC) in maintenance peritoneal dialysis(PD) patients.
MethodsA total of 111 PD patients with regularly followed up in the Peritoneal Dialysis Center of the Second Affiliated Hospital of Anhui Medical University and lateral abdominal X-ray examination were investigated.According to the presence or absence of AAC on lateral abdominal radiographs, the patients were divided into the non-calcification group(54 cases) and calcification group(57 cases).The general data, laboratory indicators and total Kt/V between two groups were compared, and the related factors of AAC were analyzed.
ResultsThe age, dialysis time, serum phosphorus and natriuretic peptide levels in calcification group were significantly higher than those in non-calcification group(P < 0.05 to P < 0.01).However, the hemoglobin level, total Kt/V, albumin level and left ventricular ejection fraction in calcification group were significantly lower than those in non-calcification group(P < 0.05 to P < 0.01).The results of Spearman multivariate correlation analysis showed that the age, dialysis time, serum phosphorus and cerebrouretic natriuretic peptide levels were positively correlated with AAC(P < 0.05 to P < 0.01), while the hemoglobin level, total Kt/V, albumin, left ventricular ejection fraction were negatively correlated with AAC(P < 0.05 to P < 0.01).The results of multivariate logistic regression analysis showed that the higher age(OR=1.116, 95%CI: 1.066-1.169, P < 0.01), lower hemoglobin(OR=0.966, 95%CI: 0.941-0.992, P < 0.05) and decrease of total Kt/V(OR=0.362, 95%CI: 0.175-0.747, P < 0.01) were the risk factors of AAC.
ConclusionsThe total Kt/V in PD patients is the independent risk factor of AAC.
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