Multivariate analysis of the influencing factors of endoscopic treatment effects in esophageal-gastro varices in cirrhosis

ObjectiveTo analyze the related factors affecting the effects of endoscopic treatment of esophageal-gastro varices, and explore the risk factors of postoperative rebleeding and strategies to improve its prognosis.

MethodsThe relevant data of 186 patients with liver cirrhosis complicated with esophagogastric varices treated with endoscopy from January 2017 to September 2020, were collected.According to the occurrence of bleeding or rebleeding within 1 year after endoscopic treatment, the patients were divided into the non-bleeding group(n=124) and bleeding group(n=62).The related factors affecting the postoperative bleeding of esophageal-gastro varices were analyzed.

ResultsThe differences of the Child-Pugh grade of liver function, varicose vein diameter, red sign, operation method, treatment times, regular follow-up, hemoglobin level, platelet count and prothrombin time(PT) between two groups were statistically significant on admission(P < 0.05 to P < 0.01).The results of multivariate logistic regression analysis showed that the Child-Pugh grade of liver function, maximum diameter of varicose veins, red sign, PT, regular follow-up and treatment times were the related independent factors affecting the bleeding after endoscopic treatment(P < 0.05 to P < 0.01).

ConclusionsThe Child-Pugh grade of liver function, varicose vein diameter, red sign and PT are the independent risk factors of rebleeding after endoscopic treatment.Strict regular follow-up and appropriate increase of treatment times can reduce the risk of rebleeding and improve the prognosis of patients.