Influencing factors of common adverse reactions of immunotherapy in patients with non-small cell lung cancer

ObjectiveTo analyze the occurrence of immunotherapy adverse reactions in patients with non-small cell lung cancer(NSCLC) and influencing factors.

MethodsThe general investigation table, the medical treatment and judgment meter and CTCAE adverse reactions survey were investigated in 110 NSCLC patients for the first time to use Pembrolizumab.

ResultsSingle factor analysis showed that smoking history, drinking history, surgery history, chemotherapy history, Chinese medicine physique were the influencing factors of fatigue; gender, smoking history, smoking index, allergy history, TNM staging, chemotherapy history, Chinese medicine physics were the influencing factors of rash.Career, allergic history, TNM grading, chemotherapy history, Chinese medicine physique were the influencing factor of itching; gender, marital status, smoking history, drinking history, allergy history, surgery history, chemotherapy history, Chinese medicine physiothema were the influencing factors of diarrhoea.Logistic regression analysis showed that, the history of drinking was the main influencing factor in which the smoking is a history of smoking.The main influencing factors of the rash occurred; variables are not the main influencing facto of itch, and the history of surgery is a diarrhea.The main influencing factors.

ConclusionsMedical staff should take predictive interventions to reduce immune-related adverse reactions.