Analysis of influencing factors and nursing strategies of infusion port-related thrombosis in chemotherapy patients with lung cancer

ObjectiveTo analyze the influencing factors of infusion port-related thrombosis in chemotherapy patients with lung cancer, and to propose nursing strategies.

MethodsA total of 158 patients with lung cancer from July 2016 to March 2019 were taken as the research objects.The influencing factors of the infusion port-related thrombosis were analyzed by univariate and unconditional multivariate logistic regression analysis.The risk factors of thrombosis related to infusion port were explored, and the predictive effect of logistic regression was verified using ROC curve.

ResultsThirty-one cases(19.6%) of infusion port-related thrombosis occurred in lung cancer chemotherapy patients.Univariate and multivariate logistic regression analysis showed that indwelling time, blood hypercoagulability status, tumor classification, and chemotherapy regimens were the main factors of infusion port-related thrombosis(P < 0.05 to P < 0.01).The multivariate logistic regression model predicted the probability P for ROC curve verification, and the AUC was 0.905(95%CI: 0.884-0.927), the sensitivity was 0.861, the specificity was 0.793, and the Youden index was 0.654.

ConclusionsInfusion port-related thrombosis in lung cancer chemotherapy patients is related to catheter indwelling time, blood hypercoagulability status, tumor classification, and chemotherapy regimens.Nurses should do a good job in screening and education of venous thromboembolism high-risk groups, establish a follow-up registration system at the infusion port, and strengthen the standardized training of nursing staff in primary hospitals and communities, so as to reduce the incidence of thrombosis in the infusion port.