ObjectiveTo investigate the prevalence of human papillomavirus(HPV) and its subtype distribution in Huaibei city, and provide reference for the prevention and treatment of cervical cancer in clinical women.
MethodsFrom March 2017 to June 2018, 3 536 samples of cervical shedding cells were screened in Huaibei Miners General Hospital, and the gene subtypes of HPV were detected by PCR-reverse pot hybridization for statistical analysis.
ResultsAmong the 3 536 samples, 655 cases were positive samples, and the detection rate of which was 18.52%.The infection rate of single subtype(12.30%) was significantly higher than that of multiple infection rate(6.22%)(P<0.01).The infection rate of high-risk subtypes was 11.59%, which was significantly higher than that of low-risk subtypes(3.62%) and mixed high-risk subtypes(3.31%)(P<0.01).Among different age groups, the highest infection rate was found in the 51-60 age group(20.39%), and the difference between single infection and multiple infection rates was statistically significant(P<0.05).The positive rate of 41-50 years old group was the highest(single for 42.07%, multiple for 34.09%).The dominant subtypes of HPV were 52, 16, 58, 44 and 40 in turn.
ConclusionsThe HPV infection rate of women in Huaibei city is 18.52%, which is mainly caused by single high-risk infection.The HPV 52, 16, and 58 are the most common infection subtypes.The women aged 41-60 years are the key objects for HPV screening.
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