YANG Jie, BI Ya-ju, LIANG Zhi-chao. Effectiveness analysis of acupoint application combined with kidney tonification and blood activation method on anti-β2 glycoprotein Ⅰ antibody and platelet function in patients with recurrent abortion[J]. Journal of Bengbu Medical University, 2023, 48(7): 932-936. DOI: 10.13898/j.cnki.issn.1000-2200.2023.07.018
    Citation: YANG Jie, BI Ya-ju, LIANG Zhi-chao. Effectiveness analysis of acupoint application combined with kidney tonification and blood activation method on anti-β2 glycoprotein Ⅰ antibody and platelet function in patients with recurrent abortion[J]. Journal of Bengbu Medical University, 2023, 48(7): 932-936. DOI: 10.13898/j.cnki.issn.1000-2200.2023.07.018

    Effectiveness analysis of acupoint application combined with kidney tonification and blood activation method on anti-β2 glycoprotein Ⅰ antibody and platelet function in patients with recurrent abortion

    • ObjectiveTo investigate the effectiveness analysis of acupoint application combined with kidney tonification and blood activation method on patients with recurrent abortion.
      MethodsA total of 90 patients with recurrent abortion were selected and randomly divided into western medicine group (group A), western medicine + triditional Chinese medicine group (group B) and western medicine + Chinese medicine comprehensive treatment group (group C), with 30 patients in each group.Group A: oral aspirin; group B: oral aspirin and triditional Chinese medicine for kidney tonification and blood activation; group C: acupoint application on the basis of group B; all until 12 weeks of pregnancy.The clinical efficacy, serum human chorionic gonadotropin (hCG), progesterone (P), anti-cardiolipin antibody (ACA), anti-β2-glycoprotein Ⅰ antibody (anti-β2-GPⅠ) and ultrasound were observed before and after treatment in the three groups.
      ResultsAfter treatment, the differences were statistically significant in the efficacy of the three groups (P < 0.05), and the efficacy of group C was higher than that of group A and group B (P < 0.05 to P < 0.01).The hCG and P were significantly higher in patients of the three groups compared with the same group before treatment (P < 0.01), and group C was significantly higher than group A and group B (P < 0.01).The positive rates of ACA and anti-β2-GPⅠ in group B and group C were lower than those before treatment in the same group (P < 0.05), and the difference between the degree of reduction in group A and before treatment was not statistically significant (P>0.05).The positive rates of ACA and anti-β2-GPⅠ between the three groups were statistically significant (P>0.05), among which, group C was lower than group A and group B (P < 0.05).The platelet function improved in all groups, the (D-D) levels were significantly lower than before treatment (P < 0.01), the D-D levels in group C were significantly lower than those in group A and group B (P < 0.01), and group B was significantly lower than group A (P < 0.01).
      ConclusionsAcupoint application combined with kidney tonification and blood activation method has significant efficacy in the treatment of patients with recurrent abortion, which can effectively improve the hormone level and platelet function of patients and increase the cure rate of patients, and is worthy of clinical application.
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