Clinical application of absorbable medical vascular sealant in coronary artery bypass grafting of unilateral internal thoracic artery: experience of a single operator

ObjectiveTo investigate the hemostatic effect of absorbable medical vascular sealant in coronary artery bypass grafting of unilateral internal thoracic artery and its influence on the transit-time flow of the bridge vessel.

MethodsSixty patients with coronary atherosclerosis heart disease were selected as study subjects, who were scheduled with coronary artery bypass grafting of unilateral internal thoracic artery in cardiopulmonary bypass under general anesthesia.The patients were divided into observation group and control group according to whether absorbable medical vascular sealant was used during surgery, with 30 cases in each group.The transit-time blood flow parameters of the bridge vessel of patients during surgery before and after the use of absorbable medical vascular sealant in the observation group were compared, and related indicators during perioperative period of patients in the two groups were compared.

ResultsThere were no statistically significant differences in average blood flow and pulsatility index of patients in the observation group before and after the use of absorbable medical vascular sealant during surgery (P>0.05).The operation time, postoperative 24-hour drainage volume and postoperative 48-hour drainage volume of patients in the observation group were lower than those in the control group (P<0.05 to P<0.01).

ConclusionsThe absorbable medical vascular sealant has no effect on the transit-time blood flow of the bridge vessel during coronary artery bypass grafting of unilateral internal thoracic artery, and can effectively stop bleeding, reduce postoperative drainage volume and shorten the operation time.