ObjectiveTo explore the relationship between the prognostic nutritional index (PNI) and coronary collateral circulation (CCC) in patients with coronary chronic total occlusion (CTO).
MethodsA total of 140 patients who underwent coronary angiography to confirm the diagnosis of CTO were selected and devided into low PNI and high PNI according to the median PNI 48, and divided into poor CCC formation group (Rentrop 0-1, n=44) and good CCC formation group (Rentrop 2-3, n=96) based on the Rentrop grading.The general clinical data and laboratory test results were compared between the two groups.Logistic regression was used to analyze the risk factors of poor CCC formation.
ResultsCompared with the high PNI group, the low PNI group had older age, more numbers of vascular lesions, higher incidences of heart failure and major cardiovascular adverse events, higher proportion of poor CCC formation, and higher scores for neutrophils, urea nitrogen, and CHA2DS2-VASc scores.The proportion of complete revascularization and previous myocardial infarction was relatively low, and the levels of white blood cells, lymphocytes, albumin, and triglycerides were lower in low PNI group, with statistical significance (P < 0.05 to P < 0.01).Compared with the good CCC formation group, the poor CCC formation group had lower albumin levels, a higher proportion of low PNI, and a higher CHA2DS2VASc scores, with statistically significant differences (P < 0.05 to P < 0.01).In multivariate regression analysis, low PNI in CTO patients was associated with poor CCC formation.
ConclusionsLow PNI was an independent risk factor of poor CCC in CTO patients.
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