ZHOU Xiao-mei, CAO Qin, JIANG Qin, SUN Wen-jie, QIAO Dan, SUN Jing, FANG Meng-tian, WANG Jiu-qiang, ZHANG Xia-wan, YANG Cong-yan. Effect of the dietary fiber diet on gastrointestinal dysfunction in patients with early enteral nutrition after craniocerebral injury[J]. Journal of Bengbu Medical University, 2023, 48(12): 1766-1770. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.031
    Citation: ZHOU Xiao-mei, CAO Qin, JIANG Qin, SUN Wen-jie, QIAO Dan, SUN Jing, FANG Meng-tian, WANG Jiu-qiang, ZHANG Xia-wan, YANG Cong-yan. Effect of the dietary fiber diet on gastrointestinal dysfunction in patients with early enteral nutrition after craniocerebral injury[J]. Journal of Bengbu Medical University, 2023, 48(12): 1766-1770. DOI: 10.13898/j.cnki.issn.1000-2200.2023.12.031

    Effect of the dietary fiber diet on gastrointestinal dysfunction in patients with early enteral nutrition after craniocerebral injury

    • ObjectiveTo investigate the effects of dietary fiber(DF) diet on gastrointestinal dysfunction in patients with early enteral nutrition after craniocerebral injury.
      MethodsA total of 90 patients with traumatic brain injury were divided into the control group(group A) and observation group(group B and group C) according to the order of admission time (30 cases in each group).Group A was treated with the enteral nutrition suspension.The group B was treated with the enteral nutrition suspension combined with low DF, and the group C was treated with the enteral nutrition suspension combined with high DF for 7 days.The incidence rates of diarrhea, constipation, vomiting/reflux and gastrointestinal bleeding were observed in the three groups.The C-reactive protein(CRP), white blood cell count(WBC) and procalcitonin (PCT) were recorded on the first, fourth and seventh day of admission.The GCS scores of three groups were recorded before and after intervention.
      ResultsThe differences of the incidence rates of gastrointestinal dysfunction among the three groups were statistically significant(P < 0.01).The incidence rate of intestinal dysfunction in group C was lower than that in group A(P < 0.05), but there was no statistical significance between group B and group C(P>0.05).The incidence rate of diarrhea in group C was lower than that in group A(P < 0.05).There was no statistical significance in inflammatory indexes among the three groups on the first day(P>0.05).On the fourth day, the level of CRP in group A was higher than that in group B and group C, and the levels of WBC and PCT in group A and group B were higher than those in group C(P < 0.01).On the seventh day, the levels of CRP in group A and group B were higher than that in group C, the WBC level in group A was higher than that in group B and group C, and the PCT level in group A was higher than that in group C(P < 0.01).After intervention, the proportion of GCS score with 7-9 points in group A was lower than that in group C(P < 0.05).
      ConclusionsDF diet can reduce the incidence rate of gastrointestinal dysfunction in patients with early enteral nutrition and inflammatory reaction of patients with craniocerebral injury, and has no effect on the change of consciousness in the short term.The effect of high DF diet is better than that of low DF diet.
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