Comparison of lauromacrogol foam and raw liquid sclerosing agent in endoscopic sclerotherapy for bleeding prone internal hemorrhoids

Objective To investigate the difference between lauromacrogol foam and raw liquid sclerosing agent in the use of endoscopic sclerotherapy for bleeding prone internal hemorrhoids.

Methods One hundred and eight patients with bleeding tendency of internal hemorrhoids were selected, and divided into laurofoam sclerosing agent group(FS group) and raw liquid sclerosing agent group(LS group). The differences of treatment effect, patient evaluation and operation process in two groups were observed.

Results At the end of treatment, the incidence artes of local bleeding, perianal pain, and perianal discomfort in the FS group were lower than those in LS group(P < 0.05 to P < 0.01). After 24 hours of surgery, the incidence rates of perianal pain and discomfort were lower, and the satisfaction was higher in the FS group than those in LS group(P < 0.01). After 2 weeks of surgery, the therapeutic effects in the FS group was better than that in LS group(P < 0.05), and there was no statistical significance in the incidence rates of perianal pain and discomfort, treatment effectiveness and patient satisfaction betwen two groups(P>0.05). After 4 weeks of operation, the differences of treatment effectiveness and satisfaction between two groups were statistically significant(P < 0.01), and there was no statistical significance in the incidence rates of perianal pain and discomfort between two groups(P>0.05). There was no statistical significance in the incidence of complications between two groups(P>0.05). The differences of the usage amount of laurofoam and total number of injection sites between two groups were statistically significant(P < 0.01).

Conclusions The clinical application value of poly(cinnamyl alcohol) foam sclerosing agent in endoscopic sclerotherapy of bleeding prone internal hemorrhoids is high.