Aapplication value of esketamine combined with serratus anterior plane block in modified radical mastectomy of breast cancer

LIU Mengya; LIU Yuan; YANG Zhen; XU Zhi; WANG Nanhai

doi:10.13898/j.cnki.issn.1000-2200.2024.11.005

Journal of Bengbu Medical University > 2024 > 49(11): 1434-1437. > DOI: 10.13898/j.cnki.issn.1000-2200.2024.11.005

LIU Mengya, LIU Yuan, YANG Zhen, XU Zhi, WANG Nanhai. Aapplication value of esketamine combined with serratus anterior plane block in modified radical mastectomy of breast cancer[J]. Journal of Bengbu Medical University, 2024, 49(11): 1434-1437. DOI: 10.13898/j.cnki.issn.1000-2200.2024.11.005

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Aapplication value of esketamine combined with serratus anterior plane block in modified radical mastectomy of breast cancer

1.
Department of Anesthesiology, , The First Affiliated Hospital of Bengbu Medical University, Bengbu Anhui 233004, China
2.
Department of Oncology, The First Affiliated Hospital of Bengbu Medical University, Bengbu Anhui 233004, China

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Received Date: May 14, 2024
Revised Date: September 29, 2024

Graphical Abstract

Abstract

Abstract

Objective
To explore the application value of esketamine combined with ultrasound-guided serratus anterior plane block(SAPB) in modified radical mastectomy of breast cancer.
Methods
A total of 60 patients aged 20-60 years and BMI 18 ~ 24.5 kg/m² scheduled by modified radical mastectomy under laryngeal mask general anesthesia were selected, and randomly divided into the observation group(group S) and control group(group C).The group C received the anterior serrated muscle plane block under ultrasound guidance and 0.25% ropivacaine as local anesthetics.On the basis of the control group C, the group S was given intravenous esketamine 0.25 mg/kg 30 min before the end of the operation.The postoperative controlled intravenous analgesia(PCIA) was given in two groups.The perioperative observation indexes, postoperative sedation, analgesia scores, adverse reactions and complication rate of SPAB were observed in two groups.
Results
The time of first analgesic pump compression in the group S was longer than that in group C, the number of analgesic pump compression after 48 h of surgery and dosage of sufentanil after 24 h and 48 h of surgery in the group S were lower than those in group C, the degree of analgesia after 3 h, 6 h and 12 h of surgery in the group S were higher than that in group C, and the total incidence rate of adverse reactions in the group S was lower than that in group C(P < 0.05).There was no statistical significance in the sedation scores after 3 h, 6 h, 12 h, 24 h and 48 h and pain scores after 24 h and 48 h of operation between two groups(P>0.05).
Conclusions
Esketamine combined with ultrasound-guided SAPB has ideal analgesic effects and less adverse reactions in modified radical mastectomy.
- breast neoplasms,
- esketamine,
- serratus anterior plane block

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References (20)

References

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Aapplication value of esketamine combined with serratus anterior plane block in modified radical mastectomy of breast cancer

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