CT perfusion imaging in preoperative grading of astrocytoma

Objective: To evaluate the role of CT perfusion imaging(CTP) in preoperative grading of astrocytoma.Methods: CTP was performed in 31 patients with astrocytioma.Forteen cases were proved to be low-grade astrocytoma and 17 cases high-grade astrocytoma.All the cases received CT and CTP examinations.The cerebral blood flow(CBF),cerebral blood volume(CBV) and permeability surface(PS) values were calculated,and the perfusion maps were statistically analyzed.Results: The CBF,CBV and PS value of the astrocytoma were higher than that of the normal brain tissue(P<0.01).The CBF,CBV and PS value of high grade astrocytoma were higher than that of low grade astrocytoma(P<0.01).There was a positive correlation among the CBF,CBV and PS value in the astrocytoma(P<0.01).Conclusions: CTP has great clinical value in preoperative grading of astrocytoma.