• 中国科技论文统计源期刊
  • 中国科技核心期刊
  • 中国高校优秀期刊
  • 安徽省优秀科技期刊
WU Hongbing, WANG Jinping, XU Hongqiang, CHEN Xiaoyi, CHANG Lina, LI Baoqi. The diagnostic value of virtual touch quantification technology for liver fibrosis grades induced by chronic hepatisis B[J]. Journal of Bengbu Medical University, 2014, 38(5): 643-645.
Citation: WU Hongbing, WANG Jinping, XU Hongqiang, CHEN Xiaoyi, CHANG Lina, LI Baoqi. The diagnostic value of virtual touch quantification technology for liver fibrosis grades induced by chronic hepatisis B[J]. Journal of Bengbu Medical University, 2014, 38(5): 643-645.

The diagnostic value of virtual touch quantification technology for liver fibrosis grades induced by chronic hepatisis B

Funds: 

Eleven five national major project funded project (2008zx10005-006)

Anhui University of traditional Chinese medicine clinical scientific research program (2012LC1-012A)

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  • Received Date: March 04, 2013
  • Objective:To study the diagnostic value of virtual touch quantification technology in liver fibrosis grades induced by chronic hepatisis B.Method:The study subjects were performed the measurements of liver shear wave velocity by using a ultrasonic instrument named ACUSON S2000,and were composed with 30 normal control and 96 patients with chronic hepatitis B.The cutoff values of shear wave velocity of different liver fibrosis stages were detected and the correlations between shear wave velocity and pathological grades of the liver were analyzed.Results:The results showed that except for the shear wave velocity values among the control group and liver fibrosis stage S0 and stage S1 groups,and between liver fibrosis stage S0 and stage S1 groups,there were significant differences about the shear wave velocity values between other groups(P0.01).Using the cutoff values of 1.38m/s,1.74 m/s,2.19 m/s and 2.53m/s for diagnosis of S1,S2,S3 and S=4,the corresponding areas under receiver operating characteristic were 0.808,0.8723,0.889 and 0.861 respectively,and the corresponding sensibilities were 75.8%,80.5%,79.2%,78.6%,the specificities were 77.3%,83.4%,84.1%,79.5% respectively.The significant positive correlations were found between the shear wave velocity values and the grade of fibrosis and inflammation(P<0.05).Conclusions:Virtual tuoch quantification technology is a new non-invasive method to evaluate liver fibrosis grades induced by chronic hepatisis B.
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