Evaluation of docetaxel use based on projection pursuit method

Objective: To evaluate the clinical application of docetaxel using projection persuit method.Methods: The evaluation criterion of docetaxel use was formulated.Two hundred and nineteen docetaxel precriptions from Jan to Mar 2014 in a tertiary hospital were statistically analyzed and discussed by projection pursuit method.Results: The effects of the medication order,pretreatment and dosage on the application assessment of docetaxel were large by the analysis of one dimension projection value.The reasonable percentage with more than 90% accounted for 89.97% by analyzing the doctor's advice comments.Among all doctor's advice comments,the lowest percentage was 86.93%.Among 78 cases,the Ci for 1 in 55 cases(70.51%),between 0.95 and 1 in 5 cases(6.41%),between 0.90 to 0.95 in 10 cases(12.82%) and between 0.85 and 0.90 in 8 cases(10.26%) were identified.Conclusions: The rationality analysis of using docetaxel by projection pursuit method can quantitatively analyze the accuracy and rationality of drug prescription,provide effective drug use programme in clinic and quality of life of patients.