Clinical significance of detecting heterotypic lymphocyte in peripheral blood

Objective:To explore the clinical significance of the increase of heterotypic lymphocyte in peripheral blood.Methods:A total of 76 peripheral blood smears which contained more than 0.05 heterotypic lymphocyte affirmed by microscopy after Wright's staining were collected.Results:The heterotypic lymphocyte exceeding 0.1 were detected in thirty-nine of the samples (51%).The ratio of heterotypic lymphocyte infected by Epstein-barr virus and cytomegalovirus increased obviously.Conclusions:There is an intimate relation between the ratio increase of heterotypic lymphocyte in peripheral blood and some diseases.Different diseases present significant differences in the number of heterotypic lymphocyte in peripheral blood.