Ultrasonographic diagnosis of thyroid nodules by multiple Logistic regression

Objective: To explore the significance of ultrasound multiple parameters in distinguishing benign and malignant thyroid nodules,and to screen the sensitive indexes for the differential diagnosis.Methods: Three hundreds and one thyroid nodules were enrolled in this study.The ultrasonograms were retrospectively studied with multiple stepwise regression analysis.Results: With stepwise regression analysis of multivariable binary logistic regression analysis,4 ultrasound evaluation indexes were enrolled:microcalcification,internal echo of nodule,integrity of capsule and nodule boundary.Conclusions: The Logistic model can help differentiate benign from malignant thyroid nodules.