Cytogenetics of sex reverse syndrome: Case repart

Objective: To analyze the possible causes of sex reverse syndrome of one female patient.Methods: Human pheripheral blood lymphocytes culture for chromosome and karyotype analysis technique were used to research into the female patient's karyotype.Results: Thirty metaphase mitotic figures were studied and the female patient's karyotype was 46,XY.Conclusions: This female patient has 46,XY male reverse syndrome;the mutation of SRY and SOX or SRY's deletion are the main causes of sex reverse syndrome.