Treatment of Kawasaki disease with intravenous immuneoglobulin in two different doses

Objective: To explore the efficacy of different doses' of IVIG in treatment of Kawasaki disease.Methods: The data of 41 cases of Kawasaki disease admitted to our hospital from 1995 to 2003 were reviewed.Results: Seventeen cases were treated with IVIG 1g/kg(400-500 mg·kg^-1·d^-1,for 2-3 days).22 cases with IVIG 2 g/kg(400 mg·kg^-1·d^-1 for 5 days).There was no obvious difference between the two groups(P=1.000) in the lasting time of fever,blood white cell count,and coronary artery dilation(CAD).Conclusions: The efficacy of two different dose of IVIG is almost equal in treatment of Kawasaki disease.We suggest that 1 g/kg IVIG be used to save the drug resource and reduce the cost.