Correlation between plasma adiponectin and brain natriuretic peptide in acute coronary syndrome patients with metabolism syndrome

Objective: To study the association between plasma adiponectin (APN) and brain natriuretic peptide (BNP)in acute coronary syndrome patients (ACS) complicated with metabolism syndrome (MS).Methods: The plasma APN and BNP in 36 cases of ACS complicated with MS,36 cases of simplex ACS and 36 healthy controls were determined by using ELISA method and rapid fluorescence-based immunoassay,respectively.Results: The plasma APN level increased significantly in both ACS with MS group and simplex ACS group compared with that of the control (P<0.01).The BNP level had a positive correlation with APN level in ACS group and ACS complicated with MS group (P<0.05).Conclusions: Plasma APN and BPN are increased in simplex ACS patients and patients with ACS complicated with MS.The change is more obvious in patients with ACS complicated with MS.Plasma APN is positively associated with BNP.BNP and APN may be related to the occurrence and development of acute coronary syndrome.High APN and BNP levels are dangerous for patients with acute coronary syndrome.