The clinical significance of serum levels of cysc detected in patients with hypertensive disorders of pregnancy

Objective: To investigate the clinical significance of serum levels of serum cystatin C(CysC) determination in patients with hypertensive disorders of pregnancy. Methods: The patients were divided into three groups(hypertensive disorders of pregnancy,healthy nonpregnancy and late pregnancy). The serum levels of CysC,creatinine,urea nitrogen and uric acid were determined,and the results were statistically analyzed. Results: The serum levels of CysC in pregnancy were higher than nonpregnancy(P < 0.01). The serum levels of CysC in serious preeclampsia were higher than hypertensive disorders of pregnancy,mild preeclampsia and late pregnancy(P < 0.01). Conclusions: The serum levels of CysC were meaningful for the diagnosis of early kidney function damage.