Study of the biocompatibility of modified polylactic acid vector with Schwann cell

Objective: To observe the biocompatibility of modified polylactic acid vector with Schwann cell.Methods: Immersed extraction of modified PLA affect to Proliferation and cytotoxicity stage of Schwann cell by MTT method,Schwann cell morphology and adhesion condition on surface of materials were observated by scanning electro microscope and Fluor spectrophotometer.Results: Cytotoxicity stage of modified polylactic acid vector were 0-1 stage,and the mumble of schwann cells and adhesion were better than unmodified PLA,but all materials were as good as culture well(P< 0.01).Conclusions: Modified polylactic acid vector have better biocompatibility with Schwann cell,and their cytotropism were improved.