Clinical effect of compound qingdai tablets, all-trans retinoic acid and chemotherapy for treatment of acute promyelocytic leukemia of complete remission

Objective: To observe the clinical effect of compound qingdai tablets,all-trans retinoic acid(ATRA) and chemotherapy for the treatment of acute promyelocytic leukemia(APL) of complete remission.Methods: Twenty-four cases of newly diagnosed APL were induced to complete remission by using compound qingdai tablets or ATRA first,then treated alternatively with compound qingdai tablets,ATRA and chemotherapy.We monitored the PML/RARα fusion genes of the patients who maintained remission for 3 years and then decided whether to stop the therapy or continue.Results: All the cases survived.The relapse rate was 8.3% and the side effect was mild.Conclusions: The therapy of sequential use of compound qingdai tablets,ATRA and chemotherapy for treatment of APL of complete remission has the advantages of good results and mild side effects.