The clinic analysis of myocardial injury in hyperbilirubinemia

Objective: To explore the expression of cardiac enzymes and cardiac troponin I(cTnI) in neonatal hyperbilirubinemia.Methods: Eighty neonates with hyperbilirubinemia and 80 neonates with physiological jaundice were divided into the hyperbilirubinemia group and control group.The serum levels of cTnI,creatine kinase,creatine kinase-MB,aspartate aminotransferase and in two groups were measured.Results: The positive rates of cTnI and creatine kinase-MB in hyperbilirubinemia group were 70.0% and 46.3%,respectively,the difference of which was statistically significant(P<0.01).The total bilirubin level was positively correlated with cTnI in hyperbilirubinemia group(P<0.01).Conclusions: High bilirubin can lead to a reversible myocardial injury.The expression of cTnI is stable,which can be used as a criteria in early diagnosis and treatment of myocardial injury.