Clinical analyses of high dose immunoglobulin in treatment of severe viral encephalitis in children

Objective: To evaluate the efficacy of high dose immunoglobulin in treatment of severe viral encephalitis in children.Methods: Thirty-eight children were divided into study group(n=16) treated with intravenous high dose immunoglobulin and control group(n=22).The clinical symptoms,physical signs and the time of hospital stay were observed and compared.Results: It took less time for the study group to bring down a fever,stop spasm and regain consciousness than it did for the control group(P<0.05 to P<0.01),and no difference was found in the time of hospital stay between the two groups(P>0.05).Conclusions: Intravenous high dose immunoglobulin can relieve brain tissue damage and is effective in treating severe viral encephalitis of children.