Analysis of the clinical features and drug sensitivity of 21 cases patients with paratyphoid A

Objective: To analyze the clinical features and drug sensitivity of paratyphoid A.Methods: Twenty-one cases of paratyphoid A were analyzed retrospectively.The clinical features and drug sensitivity were compared with the cases selected randomly in Chinese Academic Journal(CD) from 1994-1996.Results: The presentation of typical characteristics of typhoid and paratyphoid was 86.1 and 4.8 in the typhoid group and paratyphoid A group respectively;obvious toxic symptoms were observed in 62.5 of the patients in the typhoid group and 38.1 in the paratyphoid A group;The incidence of relative infrequent pulse was 36.4 and 9.5 in the typhoid group and paratyphoid A group respectively;The apathia rate was 51 in the typhoid group and 9.5 in the paratyphoid A group;The incidence rate of enlarged spleen was 12.6 and 52.9 in the typhoid group and paratyphoid A group respectively(P<0.05~P<0.01).The difference was significant.The incidence of fever,rose rash and hepatauxe was 99.1, 14.1 and 19.1 in the typhoid group and 100,9.5 and 29.4 in the paratyphoid A group,respectively;the difference was not significant (P>0.05).The sensitiveness rate of quinolones was 100 and the sensitiveness rate of the third generation ephamycins was above 90.Conclusions: Clinical symptoms of paratyphoid A are not typical.Quinolones is the first medicine for treatment of paratyphoid A,and the third generation ephamycins and chlormycetin are the second choice.