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ZHANG Li, ZHANG Cheng-shu, WANG Jun, LIN Xiao-xi, WANG Chen, WANG Wei. Treatment of proliferative hemangiomas with high dose of systemic corticosteroid[J]. Journal of Bengbu Medical University, 2007, 32(5): 525-527.
Citation: ZHANG Li, ZHANG Cheng-shu, WANG Jun, LIN Xiao-xi, WANG Chen, WANG Wei. Treatment of proliferative hemangiomas with high dose of systemic corticosteroid[J]. Journal of Bengbu Medical University, 2007, 32(5): 525-527.
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Treatment of proliferative hemangiomas with high dose of systemic corticosteroid

  • 1. Department of Plastic Surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu 233004;

  • 2. Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaotong University Medical College, Shanghai 200011, China

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  • Received Date: November 01, 2006
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  • Objective: To investigate the efficacy and complication of high dose of corticosteroid in treatment of proliferative hemangiomas of infants. Methods: The proliferative hemangioma infants were administered prednisone in the first 8 weeks according to their wight (4 mg/kg) and the dosage was decreased to 2 tablets in the 9th week and 1 tablet in the 10th week;the medicine was taken orally once every two days at 8-9 am for 10 weeks. The outcome of treatment, courses of therapy, and short and long term of side effects were analyzed. Results: The overall response rate was 90% in proliferative hemangiomas infants treated with Corticosteroid;92% of the infants entered into stable involuting stage with no serious short or long term complications after 1-2 courses. Conclusions: 1-2 courses of high dose of corticosteroids provide a safe and effective modality for treatment of proliferative hemangiomas in infants. It is worth popularizing.
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