Primary malignant lymphoma of the bilateral epididymus: Case report and review of the literature

Objective: To study the clinical and pathological features of primary malignant lymphoma of the bilateral epididymus.Methods: The surgical specimens of a 42-year-old man with primary malignant lymphoma of the bilateral epidiymus were observed by light microscopy and immunohistochemistry,and the literature was reviewed.Results: The patient presented with painless bilateral epididymal enlargement and the extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue(MALT) was diagnosed by histopathology.The expression of CD45,CD20 and CD79α in the tumor cells was positive,while the expression of CD45RO,CD3,cytokeration(CK) and placental alkaline phosphatase(PLAP) was negative.Conclusions: Primary malignant lymphoma arising in the epididymis is a rare entity.The diagnosis mainly relies on histopathological and immunohistochemical findings.