Pharmacodynamics effects of stachys floridana schuttl.ex benth polysaccharide on blood sugar in streptozotocin-induced diabetic mice

Objective:To observe the hypoglycemic effects of stachys floridana schuttl.ex benth polysaccharide(SFSBP)in hyperglycemic mice induced by streptozotocin.Methods:Forty-eight mice were randomly divided into six groups,in addition to the blank control group,intraperitoneal injection of an equal volume of saline,the other groups were intraperitoneal injection of streptozotocin 150 mg/kg to built diabetic mice model,SFSBP was given by 10 d.The blood sugar level of mice were determined by hexose kinase method.Results:SFSBP 50,100 and 200 mg/kg could significantly decrease the blood sugar level in streptozotocin-induced diabetic mice(P0.01).Conclusions:SFSBP has the hypoglycemic action on streptozotocin-induced diabetic mice.