Effect of okra capsule on renal function of patients receiving chemotherapy with csplatin

Objective:To observe the protective effect of okra capsule on the renal function of patients receiving chemotherapy with cisplatin. Methods:Sixty-eight patients who had suffered from chemical renal functional impairment and recovered, and been proved free of primary renal disease were enrolled. They were randomly divided into observation group and control group(n = 34). Both groups received chemotherapy of regular dose of cisplatin. The patients in observation group were added okra capsule, while the control group were given chemotherapy alone. The renal function of all the patients was checked regularly during the therapy session. The serum creatinine level, creatinine clearance, serum cystatin C and urine 2-mictoglobulin of the two groups were compared one month after the therapy. Results:The change of the index representing the renal function impairment was quite slight in the observation group(P0.05),while it was rather obvious in the control group 1 and 4 weeks after the chemotherapy(P0.01). Conclusions:Okra capsule has protective effect on the renal function of patients during chemotherapy with cisplatin,which can relieve the renal toxicity of cisplatin.