Effect of treatment of rickets with different dosage of vitamin D on eruption of deciduous teeth

Objective: To explore the effect of treatment of rickets with different dosage of vitamin D on eruption of the deciduous teeth.Methods: Sixty children(aged 0 to 2 years) of vitamin D deficiency rickets were randomly divided into group of pulse therapy(vitamin D₃ 300 000 IU was given intramuscularly every 4 to 6 week and repeated 2 to 3 times within 3 to 4 months) and the control group(vitamin D concentrated drops in daily doses of 2 000-4 000 IU was orally given and 400-800 IU daily after 1 month) to observe the monthly number of children with eruption.Results: The average monthly number of children with eruption in the group of pulse therapy was significantly more than those in the control group,28/32 and 15/28 respectively(P<0.01).Conclusions: The pulse therapy of vitamin D may accelerate the eruption of the deciduous teeth in the rachitic children aged between 0 and 2 years old.The rate of eruption of the deciduous teeth may be one of the sensitive indices to evaluate the curative effect of rickets.