Study of the correlation of iNOS,TNF-a and IL-1ingastric mucosa tissues in patients with Helicobacter pylori associated gastritis

To study the correlation oI inducible nitric oxide synthase(iNOS),tumor necrosis factor(TNF)andinterleukinp(ILKp)in gastric mucosa tissues in patients with Helicobacter pylori(Hp)associated gastritis. Methods:One hundredand twentyix cases oI Hp inlected chronic gastritis and 122 cases oI Hp uninlected chronic gastritis were included in the study. Thediagnosis oI chronic gastritis was established by gastroscopy and histological examination. The Hp inlection was detected by rapid ureasetest and Giemsa stainning. The levels oI TNF and ILKp were determined by immunoradiometric assay and the expression oI iNOSwas determined by immunohistochemistry.