relationship between the plasma level of high sensitivity C creactive protein,homocysteine and pulse wave velocity in patients with coronary heart disease

Objective:To observe the correlation between the plasma level of high sensitivity C creactive protein(Hs-C P),homocysteine(HCY)and pulse wave velocity(PWV)in patients with coronary heart disease(CHD).Methods:Fifty-seven CHD patients confirmed by coronary angioplasty were divided into single vessel-lesion group(14 cases) double-vessel-lesion group(26 cases)and triple-vessel-lesion group(17 cases),while 25 healthy adults were selected as control.The Hs-CrP,HCY,plasma glucose(FPG),triglyceride(TG) total cholesterol(TC),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C)and PWV were detected in each group.Results:Compared with the control,the plasma level of FPG,TG,TC,LDL-C,Hs-CrP,HCY and PWV of the CAD group increased significantly(P0.01).The plasma level of Hs-CrP,HCY and PWV increased in accordance with the number of the coronary lesion(P0.05 to P0.01).The plasma level of HCY was positively correlated with that of Hs-CrP,HCY and PWV(P0.05).Conclusions:The plasma level of Hs-CrP,HCY and PWV are high in patients with CHD and closely correlated with the degree of the coronary lesion,which may be of use in predicting the severity of the CHD.