Risk factors for cardiovascular disease in maintenance hemodialysis patients

Objective: To investigate the relationship between the uric acid and cardiovascular diseases( CVD) in patients receiving maintenance hemodialysis， and the risk factors for CVD. Methods: Ninety-seven maintenance hemodialysis patients were divided into CVD group and non-CVD group. The clinical data were collectedretrospectively and analyzed with univariate and multivariate models to find out the risk factors for CVD. Results: The level of serum uric acid in CVD group was significantly higher than that in non-CVD group( P ＜ 0. 01) ， and the duration of dialysis， fasting plasma glucose，mean arterial blood pressure( MBP) and total cholesterol( TC)levels were significantly different between the two groups( P ＜ 0. 01) ; logistic regression analysis showed that the uric acid，MBP and TC level were positively correlated with the incidence of CVD( P ＜ 0. 05 － P ＜ 0. 01) . Conclusions: In maintenance hemodialysis patients，the serum uric acid，MBP and TC levels are independent risk factors for CVD.