A simple device for blood collection by tail snipping in mice

Objective: To investigate the effects of a new simple device for blood collection by tail snipping in mice for providing a safey， convenient and economical method. Methods: The device was made by some hard paper，gauze，and two centrifuge tubes( 50 ml) ， and which were fixed on a plastic plate. The blood of 50 Kunming mice aged 6 to 8 weeks were collected by tail snipping for repeat 4 times. Results: The device was cheap， and easy to be made and handled，which could collect blood for two mice at the sametime. No mouse was disabled or dead during the experimental course. Conclusions: The device is a safe and ideal equipment for bloodcollection by tail snipping in mice.